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Clinical Research Detail
Materials collected from participants in the research study will be used to investigate a variety of topics. Specifically, the goals of the research are:
-To characterize individuals with PPA using neuropsychological testing and brain imaging
-To investigate naming and word processing problems in PPA and see how it relates to brain changes
-To increase awareness of PPA, educate others about this unique disorder and encourage more research to eventually develop a treatment
The research study lasts three days total, about seven hours each day including breaks and lunch. Days one and two are in Chicago and involve a battery of neuropsychological tests, a magnetic resonance imaging (MRI) scan and an event-related potentials (ERP) task. The third day takes place at Northwestern's main campus in Evanston, IL and involves computerized language and naming experiments, some which include voice recording and others that include ERP testing.
Sixty people with PPA and 60 age-matched control subjects will participate in this study. Participants will be asked to return two years later to compare changes between the two visits.
Out of town participants and study partners will have air travel and accommodations paid for and booked in advance by the research study. Local participants will have travel expenses compensated. Subjects will be reimbursed for meals. In addition to travel and meal costs, participants will be paid $100 per day.
Potential participants must be right handed, not claustrophobic and safe for MRI, and free of any illness or condition other than PPA that would affect their ability to participate now or in the future. Individuals not seen at Northwestern Cognitive Neurology and Alzheimer's Disease Center will need to send records (neurology, neuropsychology and imaging reports) and have a phone interview before being approved by the study director to participate.
resource entered by: ImPPAct